![]() Better family functioning and higher income have been reported to reduce the burden of the caregiver. Caregiver features, such as poor physical and mental health status, low education level, cohabitation with the patient, and female gender, are associated with a higher burden of caregiving. Patient characteristics that increase caregiver burden include neuropsychiatric symptoms, daily functional limitations, and duration of illness. Previous systemic reviews have revealed that factors associated with caregiver burden can be divided into three categories, namely, patient character, caregiver character, and family function ( Chiao et al., 2015 van den Kieboom et al., 2020). A high care burden typically also reduces the work productivity of caregivers ( Fujihara et al., 2019). The burden of caregiving can reduce the quality of life of caregivers and cause depressive symptoms ( Liew et al., 2020). Taking care of AD patients is difficult and is often associated with a high burden of care, especially over a prolonged period of time ( van den Kieboom et al., 2020). Alzheimer's disease (AD) is the most common cause of dementia ( Scheltens et al., 2016). More than 40 million people around the world are living with dementia, and the prevalence is still increasing. The dementia care team should provide personalized education and transfer patients and caregivers to appropriate resources, especially for high-risk populations. Patients with more severe dementia, neuropsychiatric symptoms, being cared for by more than two caregivers, or utilizing social resources were associated with higher ZBI scores the depressive mood of caregiver also predicted higher ZBI scores.Ĭonclusion: This longitudinal study demonstrated that caregiver burden was influenced by the underlying dementia etiology of patients. Caregivers of mixed-type dementia and frontotemporal dementia (FTD) experienced a greater burden than caregivers of AD, at 6- and 18-month follow-up. Results: Participants with Lewy body disease (LBD) had a significantly higher caregiving burden compared with those with Alzheimer's disease (AD) (β = 3.83 ± 1.47, Wald = 6.79, p = 0.009) after adjusting for patient and caregiver features. Generalized estimating equations were used for the longitudinal data analysis. The primary outcome was the change in Zarit Burden Interview (ZBI) scores. The care team performed face-to-face interviews every 6 months, for 18 months from when a diagnosis of dementia was made. Methods: This 18-month retrospective cohort study enrolled 630 patients and their caregivers from the Dementia Center of Changhua Christian Hospital. 3Department of Recreation and Holistic Wellness, Ming Dao University, Changhua, Taiwanīackground: This study aimed to elucidate the influence of dementia etiologies on the degree of caregiver burden and determine which factors predict a high caregiving burden.2Department of Nuclear Medicine, Changhua Christian Hospital, Changhua, Taiwan.1Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan.Wen-Chien Huang 1 †, Ming-Che Chang 2 †, Wen-Fu Wang 1,3 and Kai-Ming Jhang 1 *
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